When Loading the model make sure you check 'Manually Choose Model Load Parameter' for developer options, and also 'advanced settings'
Lower 'Context' if only using model for chat, 'Higher' Using tools & Agents!
Increase GPU Offload as much as you can, Use models that fit based on ram, (My new mac is 32GB) (old macs 16GB)
click load
when model loads start a chat, sometime you have to click the model again